1nrl: Difference between revisions
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[[Image:1nrl.gif|left|200px]] | [[Image:1nrl.gif|left|200px]] | ||
'''Crystal Structure of the human PXR-LBD in complex with an SRC-1 coactivator peptide and SR12813''' | {{Structure | ||
|PDB= 1nrl |SIZE=350|CAPTION= <scene name='initialview01'>1nrl</scene>, resolution 2.00Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SRL:[2-(3,5-DI-TERT-BUTYL-4-HYDROXY-PHENYL)-1-(DIETHOXY-PHOSPHORYL)-VINYL]-PHOSPHONIC ACID DIETHLYL ESTER'>SRL</scene> | |||
|ACTIVITY= | |||
|GENE= NR112 or PXR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal Structure of the human PXR-LBD in complex with an SRC-1 coactivator peptide and SR12813''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1NRL is a [ | 1NRL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NRL OCA]. | ||
==Reference== | ==Reference== | ||
Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor., Watkins RE, Davis-Searles PR, Lambert MH, Redinbo MR, J Mol Biol. 2003 Aug 22;331(4):815-28. PMID:[http:// | Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor., Watkins RE, Davis-Searles PR, Lambert MH, Redinbo MR, J Mol Biol. 2003 Aug 22;331(4):815-28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12909012 12909012] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: xenobiotic]] | [[Category: xenobiotic]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:00:44 2008'' |