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[[ | ==Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex== | ||
<StructureSection load='4dy8' size='340' side='right' caption='[[4dy8]], [[Resolution|resolution]] 1.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4dy8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DY8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DY8 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dwy|4dwy]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dy8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dy8 RCSB], [http://www.ebi.ac.uk/pdbsum/4dy8 PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Crystal structures of the hexanucleotide d(CACGCG).d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn(2+) were used in crystallization. The availability of Mn(2+) during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P2(1) and P6(5). Analysis of the molecular interactions of Mn(2+) with the Z-form duplexes shows direct coordination to the purine residues G and A. | |||
Interactions of Mn(2+) with a non-self-complementary Z-type DNA duplex.,Mandal PK, Venkadesh S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1420-6., doi: 10.1107/S1744309112041759. Epub 2012 Nov 14. PMID:23192018<ref>PMID:23192018</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
== | __TOC__ | ||
</StructureSection> | |||
[[Category: Gautham, N | [[Category: Gautham, N]] | ||
[[Category: Mandal, P K | [[Category: Mandal, P K]] | ||
[[Category: Venkadesh, S | [[Category: Venkadesh, S]] | ||
[[Category: Dna]] | [[Category: Dna]] | ||
[[Category: Manganese ion]] | [[Category: Manganese ion]] | ||
[[Category: Z-type dna double helice]] | [[Category: Z-type dna double helice]] | ||
Revision as of 17:22, 9 December 2014
Interactions of Mn2+ with a non-self-complementary Z-type DNA duplexInteractions of Mn2+ with a non-self-complementary Z-type DNA duplex
Structural highlights
Publication Abstract from PubMedCrystal structures of the hexanucleotide d(CACGCG).d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn(2+) were used in crystallization. The availability of Mn(2+) during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P2(1) and P6(5). Analysis of the molecular interactions of Mn(2+) with the Z-form duplexes shows direct coordination to the purine residues G and A. Interactions of Mn(2+) with a non-self-complementary Z-type DNA duplex.,Mandal PK, Venkadesh S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1420-6., doi: 10.1107/S1744309112041759. Epub 2012 Nov 14. PMID:23192018[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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