1na7: Difference between revisions
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[[Image:1na7.gif|left|200px]] | [[Image:1na7.gif|left|200px]] | ||
'''Crystal structure of the catalytic subunit of human protein kinase CK2''' | {{Structure | ||
|PDB= 1na7 |SIZE=350|CAPTION= <scene name='initialview01'>1na7</scene>, resolution 2.40Å | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] | |||
|GENE= | |||
}} | |||
'''Crystal structure of the catalytic subunit of human protein kinase CK2''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1NA7 is a [ | 1NA7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NA7 OCA]. | ||
==Reference== | ==Reference== | ||
Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2., Pechkova E, Zanotti G, Nicolini C, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2133-9. Epub 2003, Nov 27. PMID:[http:// | Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2., Pechkova E, Zanotti G, Nicolini C, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2133-9. Epub 2003, Nov 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14646071 14646071] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Zanotti, G.]] | [[Category: Zanotti, G.]] | ||
[[Category: ck2]] | [[Category: ck2]] | ||
[[Category: | [[Category: microcrystal]] | ||
[[Category: microfocus esrf]] | [[Category: microfocus esrf]] | ||
[[Category: protein kinase]] | [[Category: protein kinase]] | ||
[[Category: thin-film nanotechnology]] | [[Category: thin-film nanotechnology]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:54:09 2008'' | ||
Revision as of 13:54, 20 March 2008
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| , resolution 2.40Å | |||||||
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| Activity: | Non-specific serine/threonine protein kinase, with EC number 2.7.11.1 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the catalytic subunit of human protein kinase CK2
OverviewOverview
The three-dimensional crystal structure of the triple-point mutant of the catalytic subunit of human protein kinase CK2alpha has been determined at 2.4 A resolution. Microcrystals of mutant CK2 catalytic subunit were obtained by a protein-crystallization method based on thin-film nanotechnology. These microcrystals (of about 20 micro m in diameter) were used for diffraction data collection by means of the microfocus beamline at the ESRF synchrotron. A comparison between the human protein kinase CK2alpha and the corresponding enzyme from a lower organism (Zea mays) is made.
About this StructureAbout this Structure
1NA7 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2., Pechkova E, Zanotti G, Nicolini C, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2133-9. Epub 2003, Nov 27. PMID:14646071
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