1n6b: Difference between revisions

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[[Image:1n6b.gif|left|200px]]<br /><applet load="1n6b" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1n6b.gif|left|200px]]
caption="1n6b, resolution 2.30&Aring;" />
 
'''Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole'''<br />
{{Structure
|PDB= 1n6b |SIZE=350|CAPTION= <scene name='initialview01'>1n6b</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=DMZ:4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE'>DMZ</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1]
|GENE= CYP2C5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 Oryctolagus cuniculus])
}}
 
'''Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1N6B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=DMZ:'>DMZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6B OCA].  
1N6B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N6B OCA].  


==Reference==
==Reference==
Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes., Wester MR, Johnson EF, Marques-Soares C, Dansette PM, Mansuy D, Stout CD, Biochemistry. 2003 Jun 3;42(21):6370-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12767218 12767218]
Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes., Wester MR, Johnson EF, Marques-Soares C, Dansette PM, Mansuy D, Stout CD, Biochemistry. 2003 Jun 3;42(21):6370-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12767218 12767218]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pyrene hydroxylase]]
[[Category: pyrene hydroxylase]]


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