3n0t: Difference between revisions

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[[Image:3n0t.png|left|200px]]
==Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A==
 
<StructureSection load='3n0t' size='340' side='right' caption='[[3n0t]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
{{STRUCTURE_3n0t|  PDB=3n0t  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3n0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N0T FirstGlance]. <br>
===Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A===
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OPY:(3S)-4-OXO-4-PIPERIDIN-1-YLBUTANE-1,3-DIAMINE'>OPY</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jyh|3jyh]]</td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DPP2, DPP7, QPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
==About this Structure==
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_II Dipeptidyl-peptidase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.2 3.4.14.2] </span></td></tr>
[[3n0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0T OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n0t RCSB], [http://www.ebi.ac.uk/pdbsum/3n0t PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/3n0t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
__TOC__
</StructureSection>
[[Category: Dipeptidyl-peptidase II]]
[[Category: Dipeptidyl-peptidase II]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev, A]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Cossar, D.]]
[[Category: Cossar, D]]
[[Category: Crombet, L.]]
[[Category: Crombet, L]]
[[Category: Dobrovetsky, E.]]
[[Category: Dobrovetsky, E]]
[[Category: Edwards, A M.]]
[[Category: Edwards, A M]]
[[Category: Haffner, C.]]
[[Category: Haffner, C]]
[[Category: Hassell, A.]]
[[Category: Hassell, A]]
[[Category: Khutoreskaya, G.]]
[[Category: Khutoreskaya, G]]
[[Category: Pagannon, S.]]
[[Category: Pagannon, S]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Seitova, A.]]
[[Category: Seitova, A]]
[[Category: Shewchuk, L.]]
[[Category: Shewchuk, L]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Aminopeptidase]]
[[Category: Aminopeptidase]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
Line 37: Line 50:
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 12:18, 9 December 2014

Human dipeptidil peptidase DPP7 complexed with inhibitor GSK237826AHuman dipeptidil peptidase DPP7 complexed with inhibitor GSK237826A

Structural highlights

3n0t is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:DPP2, DPP7, QPP (Homo sapiens)
Activity:Dipeptidyl-peptidase II, with EC number 3.4.14.2
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3n0t, resolution 2.45Å

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OCA
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