1mu2: Difference between revisions

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[[Image:1mu2.jpg|left|200px]]<br /><applet load="1mu2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1mu2.jpg|left|200px]]
caption="1mu2, resolution 2.35&Aring;" />
 
'''CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE'''<br />
{{Structure
|PDB= 1mu2 |SIZE=350|CAPTION= <scene name='initialview01'>1mu2</scene>, resolution 2.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1MU2 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU2 OCA].  
1MU2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MU2 OCA].  


==Reference==
==Reference==
Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors., Ren J, Bird LE, Chamberlain PP, Stewart-Jones GB, Stuart DI, Stammers DK, Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14410-5. Epub 2002 Oct 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12386343 12386343]
Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors., Ren J, Bird LE, Chamberlain PP, Stewart-Jones GB, Stuart DI, Stammers DK, Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14410-5. Epub 2002 Oct 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12386343 12386343]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: GOL]]
[[Category: GOL]]
[[Category: SO4]]
[[Category: SO4]]
[[Category: aids]]
[[Category: aid]]
[[Category: drug design]]
[[Category: drug design]]
[[Category: hiv-2 reverse transcriptase]]
[[Category: hiv-2 reverse transcriptase]]
[[Category: polymerase]]
[[Category: polymerase]]


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