Purine repressor: Difference between revisions
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*Purine repressor | |||
**[[1pru]], [[1prv]] - EcPurR DBD – ''Escherichia coli'' - NMR<br /> | |||
**[[1dbq]] - EcPurR CBD + Mg - NMR<br /> | |||
**[[1jhz]] - EcPurR CBD (mutant) + Mg <br /> | |||
*Purine repressor complex with DNA and nucleotide | |||
**[[1pnr]], [[1bdi]], [[1qp0]], [[1qp4]], [[1qpz]], [[1qqb]] - EcPurR + DNA + hypoxanthine <br /> | |||
**[[1bdh]], [[2pud]], [[2pug]], [[1vpw]], [[1qp7]], [[1qqa]], [[1jfs]], [[1jft]], [[1jh9]] - EcPurR (mutant) + DNA + hypoxanthine <br /> | |||
**[[1wet]] - EcPurR + DNA + guanine <br /> | |||
**[[2pua]] - EcPurR (mutant) + DNA + methylpurine <br /> | |||
**[[2pub]], [[2pue]] - EcPurR (mutant) + DNA + adenine <br /> | |||
**[[2puc]], [[2puf]] - EcPurR (mutant) + DNA + guanine <br /> | |||
**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br /> | |||
}} | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 14:46, 4 December 2014
<StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry 1qp4)' scene=>
Purine repressor (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides.
3D structures of purine repressor3D structures of purine repressor
Updated on 04-December-2014