1mgp: Difference between revisions
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[[Image:1mgp.gif|left|200px]] | [[Image:1mgp.gif|left|200px]] | ||
'''Hypothetical protein TM841 from Thermotoga maritima reveals fatty acid binding function''' | {{Structure | ||
|PDB= 1mgp |SIZE=350|CAPTION= <scene name='initialview01'>1mgp</scene>, resolution 2.00Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=PLM:PALMITIC ACID'>PLM</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''Hypothetical protein TM841 from Thermotoga maritima reveals fatty acid binding function''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1MGP is a [ | 1MGP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MGP OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as a fatty acid-binding protein., Schulze-Gahmen U, Pelaschier J, Yokota H, Kim R, Kim SH, Proteins. 2003 Mar 1;50(4):526-30. PMID:[http:// | Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as a fatty acid-binding protein., Schulze-Gahmen U, Pelaschier J, Yokota H, Kim R, Kim SH, Proteins. 2003 Mar 1;50(4):526-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12577257 12577257] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
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[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi]] | [[Category: psi]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
[[Category: two domain structure with mixed alpha/beta structures in both | [[Category: two domain structure with mixed alpha/beta structures in both domain]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:43:11 2008'' | ||
Revision as of 13:43, 20 March 2008
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Hypothetical protein TM841 from Thermotoga maritima reveals fatty acid binding function
OverviewOverview
We determined the three-dimensional (3D) crystal structure of protein TM841, a protein product from a hypothetical open-reading frame in the genome of the hyperthermophile bacterium Thermotoga maritima, to 2.0 A resolution. The protein belongs to a large protein family, DegV or COG1307 of unknown function. The 35 kDa protein consists of two separate domains, with low-level structural resemblance to domains from other proteins with known 3D structures. These structural homologies, however, provided no clues for the function of TM841. But the electron density maps revealed clear density for a bound fatty-acid molecule in a pocket between the two protein domains. The structure indicates that TM841 has the molecular function of fatty-acid binding and may play a role in the cellular functions of fatty acid transport or metabolism.
About this StructureAbout this Structure
1MGP is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as a fatty acid-binding protein., Schulze-Gahmen U, Pelaschier J, Yokota H, Kim R, Kim SH, Proteins. 2003 Mar 1;50(4):526-30. PMID:12577257
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Single protein
- Thermotoga maritima
- BSGC, Berkeley Structural Genomics Center.
- Kim, R.
- Kim, S H.
- Pelaschier, J.
- Schulze-Gahmen, U.
- Yokota, H.
- PLM
- Berkeley structural genomics center
- Bsgc structure funded by nih
- Protein structure initiative
- Psi
- Structural genomic
- Two domain structure with mixed alpha/beta structures in both domain