3fpi: Difference between revisions

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[[Image:3fpi.png|left|200px]]
==Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase IspF complexed with Cytidine Triphosphate==
 
<StructureSection load='3fpi' size='340' side='right' caption='[[3fpi]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
{{STRUCTURE_3fpi|  PDB=3fpi  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3fpi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FPI FirstGlance]. <br>
===Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase IspF complexed with Cytidine Triphosphate===
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f6m|3f6m]]</td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ispF, y0829, YPO3360, YPTB0771, YP_0327 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>
[[3fpi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FPI OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fpi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fpi RCSB], [http://www.ebi.ac.uk/pdbsum/3fpi PDBsum], [http://www.topsan.org/Proteins/CSGID/3fpi TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/3fpi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[MECDP synthase|MECDP synthase]]
*[[MECDP synthase|MECDP synthase]]
__TOC__
</StructureSection>
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
[[Category: Yersinia pestis]]
[[Category: Yersinia pestis]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Structural genomic]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Kim, Y.]]
[[Category: Kim, Y]]
[[Category: Maltseva, N.]]
[[Category: Maltseva, N]]
[[Category: Stam, J.]]
[[Category: Stam, J]]
[[Category: Alpha-beta sandwich]]
[[Category: Alpha-beta sandwich]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Isoprene biosynthesis]]
[[Category: Isoprene biosynthesis]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Structural genomic]]
[[Category: Structural genomics of national institute of allergy and infectious disease]]

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