1mdl: Difference between revisions

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[[Image:1mdl.gif|left|200px]]<br /><applet load="1mdl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1mdl.gif|left|200px]]
caption="1mdl, resolution 1.85&Aring;" />
 
'''MANDELATE RACEMASE MUTANT K166R CO-CRYSTALLIZED WITH (R)-MANDELATE'''<br />
{{Structure
|PDB= 1mdl |SIZE=350|CAPTION= <scene name='initialview01'>1mdl</scene>, resolution 1.85&Aring;
|SITE= <scene name='pdbsite=ACT:Site+Act+Constitutes+The+Acid/Base+Catalysts+Responsible+...'>ACT</scene>, <scene name='pdbsite=CAR:Site+Car+Constitutes+The+Binding+Site+For+The+Carboxyl+G+...'>CAR</scene> and <scene name='pdbsite=MTL:Site+Mtl+Constitutes+The+Direct+Metal+Ion+Ligands'>MTL</scene>
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RMN:(R)-MANDELIC+ACID'>RMN</scene> and <scene name='pdbligand=SMN:(S)-MANDELIC ACID'>SMN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Mandelate_racemase Mandelate racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.2.2 5.1.2.2]
|GENE= MANDELATE RACEMASE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
}}
 
'''MANDELATE RACEMASE MUTANT K166R CO-CRYSTALLIZED WITH (R)-MANDELATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1MDL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=RMN:'>RMN</scene> and <scene name='pdbligand=SMN:'>SMN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Mandelate_racemase Mandelate racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.2.2 5.1.2.2] Known structural/functional Sites: <scene name='pdbsite=ACT:Site+Act+Constitutes+The+Acid/Base+Catalysts+Responsible+...'>ACT</scene>, <scene name='pdbsite=CAR:Site+Car+Constitutes+The+Binding+Site+For+The+Carboxyl+G+...'>CAR</scene> and <scene name='pdbsite=MTL:Site+Mtl+Constitutes+The+Direct+Metal+Ion+Ligands'>MTL</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDL OCA].  
1MDL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDL OCA].  


==Reference==
==Reference==
Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant., Kallarakal AT, Mitra B, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL, Biochemistry. 1995 Mar 7;34(9):2788-97. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7893690 7893690]
Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant., Kallarakal AT, Mitra B, Kozarich JW, Gerlt JA, Clifton JG, Petsko GA, Kenyon GL, Biochemistry. 1995 Mar 7;34(9):2788-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7893690 7893690]
[[Category: Mandelate racemase]]
[[Category: Mandelate racemase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: mandelate pathway]]
[[Category: mandelate pathway]]


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