Neurexin: Difference between revisions
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{{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }} | {{STRUCTURE_3bod| PDB=3bod | SIZE=400| SCENE= |right|CAPTION=Mouse neurexin 1α LNS domain with Ca+2 ion ([[3bod]]) }} | ||
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== 3D Structures of Neurexin == | == 3D Structures of Neurexin == | ||
{{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*Neurexin | |||
**[[3mw2]] – mNRXN-1α LNS domain+splice insert 4 – mouse<br /> | |||
**[[3bod]], [[3bop]] - mNRXN-1α LNS domain<br /> | |||
**[[3mw3]], [[2r1b]] - rNRXN-1α LNS domain+splice insert 4 – rat<br /> | |||
**[[2r16]] - rNRXN-1α LNS domain+Ca<br /> | |||
**[[1c4r]] - rNRXN-1α LNS domain<br /> | |||
**[[3mw4]] - mNRXN-1α LNS domain<br /> | |||
**[[2h0b]] - bNRXN-1α LNS2 domain – bovine<br /> | |||
**[[3asi]] - bNRXN-1α LNS5-EGF3-LNS6 domains<br /> | |||
**[[3poy]] - bNRXN-1α LNS2-LNS6 domains (mutant)<br /> | |||
**[[3qcw]], [[3r05]] - bNRXN-1α LNS1-LNS6 domains (mutant)<br /> | |||
**[[2r1d]] - rNRXN-1β LNS/LG domain | |||
*NRXN+Neuroligin | |||
**[[2xb6]], [[2wqz]] – rNRXN-1α LNS domain +hNLGN-4 cholinesterase domain<br /> | |||
**[[3b3q]] - hNRXN-1α LNS domain+mNLGN-4 cholinesterase domain<br /> | |||
**[[3biw]] - rNRXN-1α LNS domain+rNLGN-1 cholinesterase domain<br /> | |||
**[[3vkf]] - bNRXN-1β LNS domain+rNLGN-1 cholinesterase domain | |||
}} | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 14:34, 1 December 2014
Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6. See Neurodevelopmental Disorders.
For Structural Analysis of Neurexin, See: Neuroligin-Neurexin Interaction
3D Structures of Neurexin3D Structures of Neurexin
01-December-2014