Inosine monophosphate dehydrogenase: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
</StructureSection>


==3D structures of inosine monophosphate dehydrogenase==
==3D structures of inosine monophosphate dehydrogenase==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


===IMPDH===
*IMPDH


[[1ak5]] – TfIMPDH – ''Tritrichomonas foetus'' <br />
**[[1ak5]] – TfIMPDH – ''Tritrichomonas foetus'' <br />
[[1eep]] – IMPDH – ''Borellia burgdorferi'' <br />
**[[1eep]] – IMPDH – ''Borellia burgdorferi'' <br />
[[1zfj]] – IMPDH catalytic domain – ''Streptococcus pyogenes'' <br />
**[[1zfj]] – IMPDH catalytic domain – ''Streptococcus pyogenes'' <br />
[[1vrd]] – IMPDH – ''Thermotoga maritima'' <br />
**[[1vrd]] – IMPDH – ''Thermotoga maritima'' <br />
[[3ffs]] – CpIMPDH – ''Cryptosporidium parvum''<br />
**[[3ffs]] – CpIMPDH – ''Cryptosporidium parvum''<br />
[[3r2g]] – IMPDH – ''Legionella pneumophila'' <br />
**[[3r2g]] – IMPDH – ''Legionella pneumophila'' <br />
[[3tsb]], [[4mjm]] – BaIMPDH (mutant) – ''Bacillus anthracis'' <br />
**[[3tsb]], [[4mjm]] – BaIMPDH (mutant) – ''Bacillus anthracis'' <br />
[[4fez]] – VcIMPDH – ''Vibrio cholerae'' <br />
**[[4fez]] – VcIMPDH – ''Vibrio cholerae'' <br />
[[4avf]], [[3zfh]] – PaIMPDH – ''Pseudomonas aeruginosa'' <br />
**[[4avf]], [[3zfh]] – PaIMPDH – ''Pseudomonas aeruginosa'' <br />


*IMPDH binary complex


===IMPDH binary complex===
**[[1me8]] – TfIMPDH + ribavirin monophosphate  <br />
**[[1pvn]] – TfIMPDH catalytic domain + transition state analog <br />
**[[1me9]] – TfIMPDH + inosinic acid <br />
**[[2cu0]] – IMPDH + xanthosine monophosphate – ''Pyrococcus horikoshii''<br />
**[[3tsd]] – BaIMPDH (mutant) + xanthosine monophosphate <br />
**[[3usb]] – BaIMPDH + inosinic acid <br />
**[[4ix2]] – VcIMPDH + inosinic acid <br />
**[[4dqw]] – PaIMPDH + ATP <br />


[[1me8]] – TfIMPDH + ribavirin monophosphate  <br />
*IMPDH ternary complex
[[1pvn]] – TfIMPDH catalytic domain + transition state analog <br />
[[1me9]] – TfIMPDH + inosinic acid <br />
[[2cu0]] – IMPDH + xanthosine monophosphate – ''Pyrococcus horikoshii''<br />
[[3tsd]] – BaIMPDH (mutant) + xanthosine monophosphate <br />
[[3usb]] – BaIMPDH + inosinic acid <br />
[[4ix2]] – VcIMPDH + inosinic acid <br />
[[4dqw]] – PaIMPDH + ATP <br />
 
===IMPDH ternary complex===
 
[[1me7]] – TfIMPDH + ribavirin monophosphate + mycophenolic acid <br />
[[1lrt]] – TfIMPDH + adenine derivative + inosinic acid <br />
[[1meh]] – TfIMPDH + mycophenolic acid + inosinic acid <br />
[[1mei]] – TfIMPDH + mycophenolic acid + xanthosine monophosphate <br />
[[1mew]] – TfIMPDH + NAD + xanthosine monophosphate <br />
[[3khj]] – CpIMPDH + inhibitor + inosinic acid <br />
[[4fo4]], [[4fxs]] – VcIMPDH + mycophenolic acid + inosinic acid <br />
[[4hlv]] – VcIMPDH + NAD + inosinic acid <br />
[[4ixh]] – CpIMPDH catalytic domain + benzoxazole inhibitor + inosinic acid <br />
[[4my8]] – BaIMPDH catalytic domain (mutant) + benzoxazole inhibitor + inosinic acid <br />
[[4my1]], [[4mya]], [[4mxs]], [[4my9]] – BaIMPDH catalytic domain (mutant) + inhibitor + inosinic acid <br />
[[4mz1]] – IMPDH catalytic domain (mutant) + inhibitor + inosinic acid – ''Campylobacter jejuni''<br />
[[4af0]] – IMPDH + mycophenolic acid + inosinic acid – ''Cryptococcus neoformans''<br />


**[[1me7]] – TfIMPDH + ribavirin monophosphate + mycophenolic acid <br />
**[[1lrt]] – TfIMPDH + adenine derivative + inosinic acid <br />
**[[1meh]] – TfIMPDH + mycophenolic acid + inosinic acid <br />
**[[1mei]] – TfIMPDH + mycophenolic acid + xanthosine monophosphate <br />
**[[1mew]] – TfIMPDH + NAD + xanthosine monophosphate <br />
**[[3khj]] – CpIMPDH + inhibitor + inosinic acid <br />
**[[4fo4]], [[4fxs]] – VcIMPDH + mycophenolic acid + inosinic acid <br />
**[[4hlv]] – VcIMPDH + NAD + inosinic acid <br />
**[[4ixh]] – CpIMPDH catalytic domain + benzoxazole inhibitor + inosinic acid <br />
**[[4my8]] – BaIMPDH catalytic domain (mutant) + benzoxazole inhibitor + inosinic acid <br />
**[[4my1]], [[4mya]], [[4mxs]], [[4my9]] – BaIMPDH catalytic domain (mutant) + inhibitor + inosinic acid <br />
**[[4mz1]] – IMPDH catalytic domain (mutant) + inhibitor + inosinic acid – ''Campylobacter jejuni''<br />
**[[4af0]] – IMPDH + mycophenolic acid + inosinic acid – ''Cryptococcus neoformans''<br />
}}
== References ==
== References ==
<references/>
<references/>


[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky