1lvc: Difference between revisions

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[[Image:1lvc.jpg|left|200px]]<br /><applet load="1lvc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1lvc.jpg|left|200px]]
caption="1lvc, resolution 3.60&Aring;" />
 
'''Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP'''<br />
{{Structure
|PDB= 1lvc |SIZE=350|CAPTION= <scene name='initialview01'>1lvc</scene>, resolution 3.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene> and <scene name='pdbligand=DOT:3'ANTHRANILOYL-2'-DEOXY-ADENOSINE-5'-TRIPHOSPHATE'>DOT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1]
|GENE=
}}
 
'''Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1LVC is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=YB:'>YB</scene> and <scene name='pdbligand=DOT:'>DOT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVC OCA].  
1LVC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVC OCA].  


==Reference==
==Reference==
Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins., Shen Y, Lee YS, Soelaiman S, Bergson P, Lu D, Chen A, Beckingham K, Grabarek Z, Mrksich M, Tang WJ, EMBO J. 2002 Dec 16;21(24):6721-32. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12485993 12485993]
Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins., Shen Y, Lee YS, Soelaiman S, Bergson P, Lu D, Chen A, Beckingham K, Grabarek Z, Mrksich M, Tang WJ, EMBO J. 2002 Dec 16;21(24):6721-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12485993 12485993]
[[Category: Adenylate cyclase]]
[[Category: Adenylate cyclase]]
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: protein-protein complex]]
[[Category: protein-protein complex]]


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