Lysin: Difference between revisions
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==egg lysin == | ==egg lysin == | ||
<scene name='60/607850/ | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''><scene name='60/607850/Alpha_helixes/1'>push here to see Lysine structure</scene> | ||
== Function == | == Function == | ||
Revision as of 10:39, 24 November 2014
egg lysinegg lysin
FunctionEgg Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg.
RelevanceStructural highlightsThe structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. you can see the alpha helixes in pink. exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of ,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action.
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ReferencesReferences
The crystal structure of lysin, a fertilization protein. Shaw A1, McRee DE, Vacquier VD, Stout CD.