Nisin: Difference between revisions
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[[Image:<math>Example.jpg]][[ | [[Image:<math>Example.jpg]][[<scene name='60/607847/Nisin_lipid_complex/1'>TextToBeDisplayed</scene>]]==Nisin-lipid || complex== | ||
<StructureSection <math>[[Media:Insert formula here]]</math>load='1stp' size='340' side='right' caption='60/607847/Nisin_structure/4' scene=''> | <StructureSection <math>[[Media:Insert formula here]]</math>load='1stp' size='340' side='right' caption='60/607847/Nisin_structure/4' scene=''> | ||
This is a default text for your page '''Tal stern/Test page'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Tal stern/Test page'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
[[nisin]] is a polycylic antobacterial peptid, with 34 amino acid residues used as a food preservative. | |||
Nisin is produced by fermentation using the bacterium Lactococcus lactis. In the food industry, it is obtained from the culturing of L. lactis on natural substrates, such as milk or dextrose, and is not chemically synthesized. | |||
While in general most [[bacteriocins]] inhibit only closely related species, nisin is a rare example of a "broad-spectrum" bacteriocin effective against many Gram-positive organisms, including lactic acid bacteria (commonly associated with spoilage), Listeria monocytogenes (a known pathogen), Staphylococcus aureus, Bacillus cereus, Clostridium botulinum, etc. It is also particularly effective against spores. Gram-negative bacteria are protected by their outer membrane but may become susceptible to nisin action after a heat shock or when this is coupled with the chelator EDTA. Nisin is soluble in water and can be effective at levels nearing the parts-per-billion range. | |||
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
This is a sample scene created with SAT to <scene name='60/607847/Nisin_lipid_complex/7'>color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | |||
This is a sample scene created with SAT to <scene name= | |||
<scene name='60/607847/Nisin_lipid_complex/8'>Text Displayed On Page</scene> | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||