Catabolite control protein: Difference between revisions

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'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria.  When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA.  The latter binds to DNA operator to modulate transcription.  
'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria.  When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA.  The latter binds to DNA operator to modulate transcription.  
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==3D structures of catabolite control protein==
==3D structures of catabolite control protein==

Revision as of 16:12, 19 November 2014


Catabolite control protein (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.

Structure of catabolite control protein (grey) complex with Hpr (khaki) and sulfate (PDB entry 2fep)

Drag the structure with the mouse to rotate

3D structures of catabolite control protein3D structures of catabolite control protein

Updated on 19-November-2014

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky
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