1l7f: Difference between revisions

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[[Image:1l7f.gif|left|200px]]<br /><applet load="1l7f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1l7f.gif|left|200px]]
caption="1l7f, resolution 1.80&Aring;" />
 
'''Crystal structure of influenza virus neuraminidase in complex with BCX-1812'''<br />
{{Structure
|PDB= 1l7f |SIZE=350|CAPTION= <scene name='initialview01'>1l7f</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=BCZ:3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC+ACID'>BCZ</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18]
|GENE=
}}
 
'''Crystal structure of influenza virus neuraminidase in complex with BCX-1812'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1L7F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Unidentified_influenza_virus Unidentified influenza virus] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=BCZ:'>BCZ</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7F OCA].  
1L7F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Unidentified_influenza_virus Unidentified influenza virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7F OCA].  


==Reference==
==Reference==
Structural studies of the resistance of influenza virus neuramindase to inhibitors., Smith BJ, McKimm-Breshkin JL, McDonald M, Fernley RT, Varghese JN, Colman PM, J Med Chem. 2002 May 23;45(11):2207-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12014958 12014958]
Structural studies of the resistance of influenza virus neuramindase to inhibitors., Smith BJ, McKimm-Breshkin JL, McDonald M, Fernley RT, Varghese JN, Colman PM, J Med Chem. 2002 May 23;45(11):2207-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12014958 12014958]
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: n9 neuraminidase]]
[[Category: n9 neuraminidase]]


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