2wot: Difference between revisions

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==ALK5 IN COMPLEX WITH 4-((5,6-DIMETHYL-2-(2-PYRIDYL)-3-PYRIDYL)OXY)-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE==
==ALK5 IN COMPLEX WITH 4-((5,6-dimethyl-2-(2-pyridyl)-3-pyridyl)oxy)-N-(3,4,5-trimethoxyphenyl)pyridin-2-amine==
<StructureSection load='2wot' size='340' side='right' caption='[[2wot]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2wot' size='340' side='right' caption='[[2wot]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOT FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZZG:4-[(5,6-DIMETHYL-2,2-BIPYRIDIN-3-YL)OXY]-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE'>ZZG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZZG:4-[(5,6-DIMETHYL-2,2-BIPYRIDIN-3-YL)OXY]-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE'>ZZG</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1py5|1py5]], [[1ias|1ias]], [[1b6c|1b6c]], [[1vjy|1vjy]], [[1rw8|1rw8]], [[2wou|2wou]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1py5|1py5]], [[1ias|1ias]], [[1b6c|1b6c]], [[1vjy|1vjy]], [[1rw8|1rw8]], [[2wou|2wou]]</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wot RCSB], [http://www.ebi.ac.uk/pdbsum/2wot PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wot RCSB], [http://www.ebi.ac.uk/pdbsum/2wot PDBsum]</span></td></tr>
<table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Debreczeni, J E.]]
[[Category: Debreczeni, J E]]
[[Category: Dishington, A P.]]
[[Category: Dishington, A P]]
[[Category: Finlay, R.]]
[[Category: Finlay, R]]
[[Category: Gingell, H J.]]
[[Category: Gingell, H J]]
[[Category: Goldberg, F W.]]
[[Category: Goldberg, F W]]
[[Category: Norman, R A.]]
[[Category: Norman, R A]]
[[Category: Powell, S J.]]
[[Category: Powell, S J]]
[[Category: Roberts, A L.]]
[[Category: Roberts, A L]]
[[Category: Roberts, N J.]]
[[Category: Roberts, N J]]
[[Category: Ward, R A.]]
[[Category: Ward, R A]]
[[Category: Wickson, K F.]]
[[Category: Wickson, K F]]
[[Category: Alk5]]
[[Category: Alk5]]
[[Category: Aortic aneurysm]]
[[Category: Aortic aneurysm]]

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