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Aldehyde dehydrogenase: Difference between revisions

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*NAD-dependent  ALDH
*NAD-dependent  ALDH


***[[2w8n]], [[2w8o]], [[2w8r]] – Succinate–semi-hALDH family 5<BR />
**[[2w8n]], [[2w8o]], [[2w8r]] – Succinate–semi-hALDH family 5<BR />
***[[2w8p]] - Succinate–semi-hALDH family 5 (mutant) <BR />
**[[2w8p]] - Succinate–semi-hALDH family 5 (mutant) <BR />
***[[3r31]] – Betaine-ALDH – ''Agrobacterium tumefaciens''<BR />
**[[3r31]] – Betaine-ALDH – ''Agrobacterium tumefaciens''<BR />
***[[3ed6]], [[4mpb]], [[4nu9]] - Betaine-SaALDH  – ''Staphylococcus aureus''<BR />
**[[3ed6]], [[4mpb]], [[4nu9]] - Betaine-SaALDH  – ''Staphylococcus aureus''<BR />
***[[1a4s]] - Betaine-cALDH - cod<BR />
**[[1a4s]] - Betaine-cALDH - cod<BR />
***[[3llg]], [[3tz6]], [[3vos]] – Aspartate-semi-MtALDH<BR />   
**[[3llg]], [[3tz6]], [[3vos]] – Aspartate-semi-MtALDH<BR />   
***[[2cq8]] - Formyltetrahydrofolate-hALDH PP-binding domain - NMR<BR />
**[[2cq8]] - Formyltetrahydrofolate-hALDH PP-binding domain - NMR<BR />
***[[2nac]] – Formate-PsALDH<BR />
**[[2nac]] – Formate-PsALDH<BR />
***[[3i44]] – ALDH – ''Bartonella henselae''<BR />
**[[3i44]] – ALDH – ''Bartonella henselae''<BR />
***[[3ek1]] – ALDH – ''Brucella melitensis''<br />
**[[3ek1]] – ALDH – ''Brucella melitensis''<br />
***[[3ros]] – ALDH – ''Lactobacillus acidophilus''<br />
**[[3ros]] – ALDH – ''Lactobacillus acidophilus''<br />
***[[3r64]] – ALDH – ''Corynebacterium glutamicum''<br />
**[[3r64]] – ALDH – ''Corynebacterium glutamicum''<br />
***[[3rhe]] – Benzaldehyde-ALDH – ''Legionella pneumophila''<br />
**[[3rhe]] – Benzaldehyde-ALDH – ''Legionella pneumophila''<br />
***[[3u4j]], [[4i3t]] – SmALDH – ''Sinorhizobium meliloti''
**[[3u4j]], [[4i3t]] – SmALDH – ''Sinorhizobium meliloti''


**Binary complexes
*NAD-dependent  ALDH binary complexes


***[[2w8q]] - Succinate–semi-hALDH family 5 + succinic acid<BR />
**[[2w8q]] - Succinate–semi-hALDH family 5 + succinic acid<BR />
***[[3fg0]], [[4mpy]], [[4nea]] - Betaine-SaALDH + NAD<BR />
**[[3fg0]], [[4mpy]], [[4nea]] - Betaine-SaALDH + NAD<BR />
***[[4ni4]] - Betaine-SaALDH (mutant) + NAD<br />
**[[4ni4]] - Betaine-SaALDH (mutant) + NAD<br />
***[[1bpw]] - Betaine-cALDH + NAD<BR />  
**[[1bpw]] - Betaine-cALDH + NAD<BR />  
***[[2j6l]] – Aminoadipate-semi-hALDH family 7 + NAD<BR />
**[[2j6l]] – Aminoadipate-semi-hALDH family 7 + NAD<BR />
***[[2cfi]] - Formyltetrahydrofolate-hALDH hydrolase domain + formyltetrahydropterin<BR />
**[[2cfi]] - Formyltetrahydrofolate-hALDH hydrolase domain + formyltetrahydropterin<BR />
***[[2nad]] - Formate-PsALDH + NAD – ''Pseudomonas''<BR />
**[[2nad]] - Formate-PsALDH + NAD – ''Pseudomonas''<BR />
***[[1bi9]] – Retinal-rALDH2 + NAD<BR />  
**[[1bi9]] – Retinal-rALDH2 + NAD<BR />  
***[[3l4p]], [[1sij]] – ALDH + AsO3 – ''Desulfovibrio gigas''<br />
**[[3l4p]], [[1sij]] – ALDH + AsO3 – ''Desulfovibrio gigas''<br />
***[[4a0m]] – spALDH + NAD – spinach<br />
**[[4a0m]] – spALDH + NAD – spinach<br />
***[[3iwk]] – amino-ALDH + NAD – pea<br />
**[[3iwk]] – amino-ALDH + NAD – pea<br />
***[[3ju8]] - Succinylglutamic–semi-PaALDH + NAD – ''Pseudomonas aeruginosa''<br />
**[[3ju8]] - Succinylglutamic–semi-PaALDH + NAD – ''Pseudomonas aeruginosa''<br />
***[[4c3s]] - ALDH + NAD – ''Clostridium phytofermentans''<br />
**[[4c3s]] - ALDH + NAD – ''Clostridium phytofermentans''<br />
***[[4i3u]] – SmALDH + phosphonoacetaldehyde<br />
**[[4i3u]] – SmALDH + phosphonoacetaldehyde<br />


**Ternary complexes
*NAD-dependent  ALDH ternary complexes


***[[2gsd]] – Formate-ALDH + NAD + azide – ''Moraxella''<BR />
**[[2gsd]] – Formate-ALDH + NAD + azide – ''Moraxella''<BR />
***[[1nvm]] – Acetaldehyde-PsALDH + 4-hydroxy-oxovalerate aldolase + NAD<BR />  
**[[1nvm]] – Acetaldehyde-PsALDH + 4-hydroxy-oxovalerate aldolase + NAD<BR />  
***[[1llu]] - PaALDH + NAD + alcohol<br />
**[[1llu]] - PaALDH + NAD + alcohol<br />
***[[4i3v]], [[4i3w]] – SmALDH + aldehyde derivative + NAD<br />
**[[4i3v]], [[4i3w]] – SmALDH + aldehyde derivative + NAD<br />
***[[4i3x]] – SmALDH + phosphonoacete + NAD<br />
**[[4i3x]] – SmALDH + phosphonoacete + NAD<br />


*NADP-dependent  ALDH
*NADP-dependent  ALDH


***[[3k2w]] - Betaine-ALDH – ''Pseudoalteromonas atlantica''<BR />
**[[3k2w]] - Betaine-ALDH – ''Pseudoalteromonas atlantica''<BR />
***[[2hg2]], [[2opx]] – Lactaldehyde-EcALDH <BR />
**[[2hg2]], [[2opx]] – Lactaldehyde-EcALDH <BR />
***[[2o2p]] – Formyltetrahydrofolate-rALDH C-terminal<br />
**[[2o2p]] – Formyltetrahydrofolate-rALDH C-terminal<br />
***[[2y51]], [[2y52]], [[2y53]], [[2y5d]] – BxALDH (mutant) – ''Burkholderia xenovorans''<br />
**[[2y51]], [[2y52]], [[2y53]], [[2y5d]] – BxALDH (mutant) – ''Burkholderia xenovorans''<br />
***[[3ifg]], [[3ifh]] - Succinate–semi-ALDH – ''Burkholderia pseudomallei''<br />
**[[3ifg]], [[3ifh]] - Succinate–semi-ALDH – ''Burkholderia pseudomallei''<br />
***[[3rh9]] - Succinate–semi-ALDH – ''Marinobacter aquaeolei''<br />
**[[3rh9]] - Succinate–semi-ALDH – ''Marinobacter aquaeolei''<br />
***[[3uw3]] - aspartate–semi-ALDH – ''Burkholderia thailandensis''<br />
**[[3uw3]] - aspartate–semi-ALDH – ''Burkholderia thailandensis''<br />
***[[3v4c]] - SmALDH
**[[3v4c]] - SmALDH


**Binary complexes
*NADP-dependent  ALDH binary complexes


***[[2wox]], [[2wme]], [[2xdr]], [[3zqa]] - Betaine-PaALDH + NADP<BR />   
**[[2wox]], [[2wme]], [[2xdr]], [[3zqa]] - Betaine-PaALDH + NADP<BR />   
***[[3lv1]] – Benzaldehyde-PpALDH3 + NADP – ''Pseudomonas putida''<BR />
**[[3lv1]] – Benzaldehyde-PpALDH3 + NADP – ''Pseudomonas putida''<BR />
***[[2ilu]] - Lactaldehyde-EcALDH + NADP<BR />
**[[2ilu]] - Lactaldehyde-EcALDH + NADP<BR />
***[[3rhd]] - Lactaldehyde-MjALDH + NADP - ''Methanocaldococcus jannaschii''<br />
**[[3rhd]] - Lactaldehyde-MjALDH + NADP - ''Methanocaldococcus jannaschii''<br />
***[[2o2q]], [[2o2r]] - Formyltetrahydrofolate-rALDH C-terminal + NADP<BR />
**[[2o2q]], [[2o2r]] - Formyltetrahydrofolate-rALDH C-terminal + NADP<BR />
***[[3b4w]] - MtALDH + NADP – ''Mycobacterium tuberculosis''<BR />
**[[3b4w]] - MtALDH + NADP – ''Mycobacterium tuberculosis''<BR />
***[[1eyy]], [[1ez0]] – ALDH + NADP – ''Vibrio harveyi''<br />
**[[1eyy]], [[1ez0]] – ALDH + NADP – ''Vibrio harveyi''<br />
***[[3jz4]] - Succinate–semi-EcALDH + NADP<br />
**[[3jz4]] - Succinate–semi-EcALDH + NADP<br />
***[[3hsk]] - aspartate–semi-ALDH + NADP – ''Candida albicans''<br />
**[[3hsk]] - aspartate–semi-ALDH + NADP – ''Candida albicans''<br />
***[[4h73]] - ALDH + NADP – ''Pyrobaculum''<br />
**[[4h73]] - ALDH + NADP – ''Pyrobaculum''<br />


**Ternary complexes
*NADP-dependent  ALDH ternary complexes


***[[3lns]] - Benzaldehyde-PpALDH3 + NADP + benzoate<BR />
**[[3lns]] - Benzaldehyde-PpALDH3 + NADP + benzoate<BR />
***[[2imp]] - Lactaldehyde-EcALDH + NADH + lactate<BR />
**[[2imp]] - Lactaldehyde-EcALDH + NADH + lactate<BR />
***[[2vro]] – BxALDH + NADP + alcohol  
**[[2vro]] – BxALDH + NADP + alcohol  




***[[3k9d]] – ALDH – ''Listeria monocytogenes''
**[[3k9d]] – ALDH – ''Listeria monocytogenes''


*Antiquitin
*Antiquitin

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman
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