3ckx: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ckx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CKX FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ckx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CKX FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ckw|3ckw]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ckw|3ckw]]</td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STK24, MST3, STK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STK24, MST3, STK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ckx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ckx RCSB], [http://www.ebi.ac.uk/pdbsum/3ckx PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3ckx TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ckx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ckx RCSB], [http://www.ebi.ac.uk/pdbsum/3ckx PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3ckx TOPSAN]</span></td></tr>
<table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Antonysamy, S S.]]
[[Category: Antonysamy, S S]]
[[Category: Buchanan, S.]]
[[Category: Buchanan, S]]
[[Category: Burley, S K.]]
[[Category: Burley, S K]]
[[Category: Chau, F.]]
[[Category: Chau, F]]
[[Category: Feil, I.]]
[[Category: Feil, I]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Sauder, J M.]]
[[Category: Sauder, J M]]
[[Category: Wu, L.]]
[[Category: Wu, L]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Mst3]]
[[Category: Mst3]]
[[Category: New york sgx research center for structural genomic]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Nysgxrc]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Protein kinase]]
[[Category: Protein kinase]]
[[Category: Protein structure initiative]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Staurosporine]]
[[Category: Staurosporine]]
[[Category: Sterile 20-like kinase]]
[[Category: Sterile 20-like kinase]]
[[Category: Stk24]]
[[Category: Stk24]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 16:09, 6 November 2014

Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporineCrystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine

Structural highlights

3ckx is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Gene:STK24, MST3, STK3 (Homo sapiens)
Activity:Non-specific serine/threonine protein kinase, with EC number 2.7.11.1
Resources:FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3ckx, resolution 2.70Å

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OCA