Telomerase 3D structures: Difference between revisions

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[[Image:Tert.png|left|200px|thumb|Structure of the catalytic subunit of telomerase, TERT, [[3du5]]]]
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Telomerase]]
{{STRUCTURE_2r4g|  PDB=2r4g  | SIZE=400| SCENE= |right|CAPTION=RNA-binding domain of telomerase complex with Br- ions, [[2r4g]] }}


[[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres.  It carries its own RNA.  The human TEL is composed of 2 [[Telomerase Reverse Transcriptase]] (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules.  For additional details see [[ Catalytic Subunit of T. Castaneum TERT Polymerase]].
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== 3D Structures of Telomerase ==
<br/>
[[3kyl]], [[3du5]], [[3du6]] – TERT+DNA – ''Tribolium castaneum''<br />
[[3kyl]], [[3du5]], [[3du6]] – TERT+DNA – ''Tribolium castaneum''<br />
[[2r4g]] – TtTERT RNA binding domain – ''Tetrahymena thermophila''<br />
[[2r4g]] – TtTERT RNA binding domain – ''Tetrahymena thermophila''<br />
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[[Category:Topic Page]]
[[Category:Topic Page]]
[[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres.  It carries its own RNA.  The human TEL is composed of 2 [[Telomerase Reverse Transcriptase]] (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules.  For additional details see [[ Catalytic Subunit of T. Castaneum TERT Polymerase]].

Revision as of 07:34, 6 November 2014

Updated on 06-November-2014 - For a general description of the protein see Telomerase

3kyl, 3du5, 3du6 – TERT+DNA – Tribolium castaneum
2r4g – TtTERT RNA binding domain – Tetrahymena thermophila
2b2a – TtTERT (mutant)
2fey - TtTERC RNA P2b hairpin – NMR
1q75, 2k96 – hTERC RNA P2b hairpin (mutant) – human – NMR
2k95 - hTERC RNA P2b hairpin – NMR
2qh2 - hTERC RNA CR7– NMR
1na2, 1ymo - hTERC RNAstem loop IV– NMR
1z31 - hTERC RNA Pj6 hairpin – NMR


Telomerase (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 Telomerase Reverse Transcriptase (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. For additional details see Catalytic Subunit of T. Castaneum TERT Polymerase.

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Alexander Berchansky, Michal Harel, Jaime Prilusky