4qqc: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 1: Line 1:
'''Unreleased structure'''
==Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations==
 
<StructureSection load='4qqc' size='340' side='right' caption='[[4qqc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
The entry 4qqc is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4qqc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQC FirstGlance]. <br>
Authors: Huang, Z., Mohammadi, M.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=37O:N-(4-{[3-(3,5-DIMETHOXYPHENYL)-7-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-2-OXO-3,4-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1(2H)-YL]METHYL}PHENYL)PROPANAMIDE'>37O</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r6v|4r6v]]</td></tr>
Description: Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qqc RCSB], [http://www.ebi.ac.uk/pdbsum/4qqc PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Huang, Z.]]
[[Category: Mohammadi, M.]]
[[Category: Cell signaling]]
[[Category: Kinase domain fold]]
[[Category: Phosphotransferase]]
[[Category: Plasmamembrane]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 14:30, 29 October 2014

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper MutationsCrystal Structure of FGF Receptor (FGFR) 4 Kinase Domain in Complex with FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations

Structural highlights

4qqc is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Receptor protein-tyrosine kinase, with EC number 2.7.10.1
Resources:FirstGlance, OCA, RCSB, PDBsum

4qqc, resolution 2.40Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=4qqc&oldid=2048586"