1jox: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1jox.gif|left|200px]] | [[Image:1jox.gif|left|200px]] | ||
'''NMR Structure of the LP5.1 Hairpin from Bacillus RNase P RNA Refined with Residual Dipolar Couplings''' | {{Structure | ||
|PDB= 1jox |SIZE=350|CAPTION= <scene name='initialview01'>1jox</scene> | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''NMR Structure of the LP5.1 Hairpin from Bacillus RNase P RNA Refined with Residual Dipolar Couplings''' | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
1JOX is a [ | 1JOX is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JOX OCA]. | ||
==Reference== | ==Reference== | ||
Structure of the UGAGAU hexaloop that braces Bacillus RNase P for action., Leeper TC, Martin MB, Kim H, Cox S, Semenchenko V, Schmidt FJ, Van Doren SR, Nat Struct Biol. 2002 May;9(5):397-403. PMID:[http:// | Structure of the UGAGAU hexaloop that braces Bacillus RNase P for action., Leeper TC, Martin MB, Kim H, Cox S, Semenchenko V, Schmidt FJ, Van Doren SR, Nat Struct Biol. 2002 May;9(5):397-403. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11927952 11927952] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Doren, S R.Van.]] | [[Category: Doren, S R.Van.]] | ||
| Line 21: | Line 30: | ||
[[Category: ugnrau]] | [[Category: ugnrau]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:06:23 2008'' | ||
Revision as of 13:06, 20 March 2008
| |||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
NMR Structure of the LP5.1 Hairpin from Bacillus RNase P RNA Refined with Residual Dipolar Couplings
OverviewOverview
Long-range interactions involving the P5.1 hairpin of Bacillus RNase P RNA are thought to form a structural truss to support RNA folding and activity. We determined the structure of this element by NMR and refined the structure using residual dipolar couplings from a sample weakly oriented in a dilute liquid crystalline mixture of polyethylene glycol and hexanol. Dipolar coupling refinement improved the global precision of the structure from 1.5 to 1.2 A (to the mean), revised the bend angle between segments of the P5.1 stem and corroborated the structure of the loop region. The UGAGAU hexaloop of P5.1 contains two stacks of bases on opposite sides of the loop, distinguishing it from GNRA tetraloops. The unusual conformation of the juxtaposed uracil residues within the hexaloop may explain their requirement in transactivation assays.
About this StructureAbout this Structure
1JOX is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
ReferenceReference
Structure of the UGAGAU hexaloop that braces Bacillus RNase P for action., Leeper TC, Martin MB, Kim H, Cox S, Semenchenko V, Schmidt FJ, Van Doren SR, Nat Struct Biol. 2002 May;9(5):397-403. PMID:11927952
Page seeded by OCA on Thu Mar 20 12:06:23 2008