VP24: Difference between revisions
Wally Novak (talk | contribs) mNo edit summary |
Wally Novak (talk | contribs) mNo edit summary |
||
| Line 18: | Line 18: | ||
The Ebola and Marburg VP24 proteins are 30% identical. They share a similar pyramidal shaped domain, as well as a few structures. Both viruses have two highly conserved pockets underneath the "pyramid's" base. Additionally, the N termini of Ebola (Zaire) and the Marburg virus are very similar in function. They are used by the for proper nucleocapsid functioning. | The Ebola and Marburg VP24 proteins are 30% identical. They share a similar pyramidal shaped domain, as well as a few structures. Both viruses have two highly conserved pockets underneath the "pyramid's" base. Additionally, the N termini of Ebola (Zaire) and the Marburg virus are very similar in function. They are used by the for proper nucleocapsid functioning. | ||
<scene name='60/602719/ | <scene name='60/602719/Chain_b/1'>Ebola Domain</scene> (Reston) | ||
There are a few structural characteristics only found in the Ebola viruses. At the top of the pyramidal domain, there are α helices present which are thought to interact with the α karyopherin. An α helix formed by the N-terminus runs from the top of the "pyramid" to one of the pockets located underneath the "pyramid." | There are a few structural characteristics only found in the Ebola viruses. At the top of the pyramidal domain, there are α helices present which are thought to interact with the α karyopherin. An α helix formed by the N-terminus runs from the top of the "pyramid" to one of the pockets located underneath the "pyramid." | ||