2htt: Difference between revisions

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-[[Image:2htt.png|left|200px]]
+==Ruthenium Hexammine ion interactions with Z-DNA==
+<StructureSection load='2htt' size='340' side='right' caption='[[2htt]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTT FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NRU:RUTHENIUM+(III)+HEXAAMINE+ION'>NRU</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hto|2hto]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2htt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2htt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2htt RCSB], [http://www.ebi.ac.uk/pdbsum/2htt PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity.
-{{STRUCTURE_2htt|  PDB=2htt  |  SCENE=  }}
+Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080<ref>PMID:18084080</ref>
-===Ruthenium Hexammine ion interactions with Z-DNA===
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-{{ABSTRACT_PUBMED_18084080}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA].
+</StructureSection>
 [[Category: Bharanidharan, D.]]
 [[Category: Gautham, N.]]