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[[Image:1jap.gif|left|200px]]<br /><applet load="1jap" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1jap.gif|left|200px]]
caption="1jap, resolution 1.82&Aring;" />
 
'''COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)'''<br />
{{Structure
|PDB= 1jap |SIZE=350|CAPTION= <scene name='initialview01'>1jap</scene>, resolution 1.82&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34]
|GENE=
}}
 
'''COMPLEX OF PRO-LEU-GLY-HYDROXYLAMINE WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1JAP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=HOA:'>HOA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAP OCA].  
1JAP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAP OCA].  


==Reference==
==Reference==
The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity., Bode W, Reinemer P, Huber R, Kleine T, Schnierer S, Tschesche H, EMBO J. 1994 Mar 15;13(6):1263-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8137810 8137810]
The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity., Bode W, Reinemer P, Huber R, Kleine T, Schnierer S, Tschesche H, EMBO J. 1994 Mar 15;13(6):1263-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8137810 8137810]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Neutrophil collagenase]]
[[Category: Neutrophil collagenase]]
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[[Category: ZN]]
[[Category: ZN]]
[[Category: metalloprotease]]
[[Category: metalloprotease]]
[[Category: metzincins]]
[[Category: metzincin]]
[[Category: zinc-endopeptidase]]
[[Category: zinc-endopeptidase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:00:47 2008''

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