1iiq: Difference between revisions

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-[[Image:1iiq.gif|left|200px]]<br /><applet load="1iiq" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1iiq.gif|left|200px]]
-caption="1iiq, resolution 1.83&Aring;" />
-'''CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR'''<br />
+ {{Structure
+|PDB= 1iiq |SIZE=350|CAPTION= <scene name='initialview01'>1iiq</scene>, resolution 1.83&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
+|GENE=
+}}
+'''CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH A HYDROXYETHYLAMINE PEPTIDOMIMETIC INHIBITOR'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-IIQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_-_1 Human immunodeficiency virus - 1] with <scene name='pdbligand=NH2:'>NH2</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIQ OCA].
+IIQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_-_1 Human immunodeficiency virus - 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIQ OCA].
 ==Reference==
-Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor., Dohnalek J, Hasek J, Duskova J, Petrokova H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlacek J, Fabry M, J Med Chem. 2002 Mar 28;45(7):1432-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11906284 11906284]
+Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor., Dohnalek J, Hasek J, Duskova J, Petrokova H, Hradilek M, Soucek M, Konvalinka J, Brynda J, Sedlacek J, Fabry M, J Med Chem. 2002 Mar 28;45(7):1432-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11906284 11906284]
 [[Category: HIV-1 retropepsin]]
 [[Category: Human immunodeficiency virus - 1]]
@@ Line 28: / Line 37: @@
 [[Category: hiv]]
 [[Category: inhibitor]]
-[[Category: peptidomimetics]]
+[[Category: peptidomimetic]]
 [[Category: protease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:12:15 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:50:52 2008''