1idt: Difference between revisions

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OCA

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-[[Image:1idt.jpg|left|200px]]<br /><applet load="1idt" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1idt.jpg|left|200px]]
-caption="1idt, resolution 2.0&Aring;" />
-'''STRUCTURAL STUDIES ON A PRODRUG-ACTIVATING SYSTEM-CB1954 AND FMN-DEPENDENT NITROREDUCTASE'''<br />
+ {{Structure
+|PDB= 1idt |SIZE=350|CAPTION= <scene name='initialview01'>1idt</scene>, resolution 2.0&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene> and <scene name='pdbligand=CB1:5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE'>CB1</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34]
+|GENE= NFNB OR NFSI OR NFSB OR NTR OR DPRA OR B0578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+}}
+'''STRUCTURAL STUDIES ON A PRODRUG-ACTIVATING SYSTEM-CB1954 AND FMN-DEPENDENT NITROREDUCTASE'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-IDT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=FMN:'>FMN</scene> and <scene name='pdbligand=CB1:'>CB1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IDT OCA].
+IDT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IDT OCA].
 ==Reference==
-Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form., Johansson E, Parkinson GN, Denny WA, Neidle S, J Med Chem. 2003 Sep 11;46(19):4009-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12954054 12954054]
+Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form., Johansson E, Parkinson GN, Denny WA, Neidle S, J Med Chem. 2003 Sep 11;46(19):4009-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12954054 12954054]
 [[Category: 6,7-dihydropteridine reductase]]
 [[Category: Escherichia coli]]
@@ Line 24: / Line 33: @@
 [[Category: prodrug]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:10:54 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:49:02 2008''