1h74: Difference between revisions

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[[Image:1h74.gif|left|200px]]<br /><applet load="1h74" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1h74.gif|left|200px]]
caption="1h74, resolution 1.9&Aring;" />
 
'''CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE'''<br />
{{Structure
|PDB= 1h74 |SIZE=350|CAPTION= <scene name='initialview01'>1h74</scene>, resolution 1.9&Aring;
|SITE= <scene name='pdbsite=AC1:ILE+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene>, <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=SAP:ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE'>SAP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Homoserine_kinase Homoserine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.39 2.7.1.39]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ILE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1H74 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ILE:'>ILE</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=SAP:'>SAP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Homoserine_kinase Homoserine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.39 2.7.1.39] Known structural/functional Site: <scene name='pdbsite=AC1:ILE+Binding+Site+For+Chain+D'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H74 OCA].  
1H74 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H74 OCA].  


==Reference==
==Reference==
Structural basis for the catalysis and substrate specificity of homoserine kinase., Krishna SS, Zhou T, Daugherty M, Osterman A, Zhang H, Biochemistry. 2001 Sep 11;40(36):10810-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11535056 11535056]
Structural basis for the catalysis and substrate specificity of homoserine kinase., Krishna SS, Zhou T, Daugherty M, Osterman A, Zhang H, Biochemistry. 2001 Sep 11;40(36):10810-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11535056 11535056]
[[Category: Homoserine kinase]]
[[Category: Homoserine kinase]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: transferase]]
[[Category: transferase]]


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