1h2z: Difference between revisions

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[[Image:1h2z.jpg|left|200px]]<br /><applet load="1h2z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1h2z.jpg|left|200px]]
caption="1h2z, resolution 1.65&Aring;" />
 
'''PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND SUC-GLY-PRO'''<br />
{{Structure
|PDB= 1h2z |SIZE=350|CAPTION= <scene name='initialview01'>1h2z</scene>, resolution 1.65&Aring;
|SITE= <scene name='pdbsite=AS1:Gol+Binding+Site+For+Chain+A'>AS1</scene>
|LIGAND= <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Prolyl_oligopeptidase Prolyl oligopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.26 3.4.21.26]
|GENE=
}}
 
'''PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND SUC-GLY-PRO'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1H2Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=SIN:'>SIN</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prolyl_oligopeptidase Prolyl oligopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.26 3.4.21.26] Known structural/functional Site: <scene name='pdbsite=AS1:Gol+Binding+Site+For+Chain+A'>AS1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H2Z OCA].  
1H2Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H2Z OCA].  


==Reference==
==Reference==
Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site., Szeltner Z, Rea D, Renner V, Fulop V, Polgar L, J Biol Chem. 2002 Nov 8;277(45):42613-22. Epub 2002 Aug 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12202494 12202494]
Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site., Szeltner Z, Rea D, Renner V, Fulop V, Polgar L, J Biol Chem. 2002 Nov 8;277(45):42613-22. Epub 2002 Aug 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12202494 12202494]
[[Category: Prolyl oligopeptidase]]
[[Category: Prolyl oligopeptidase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: serine protease]]
[[Category: serine protease]]


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