1aw6: Difference between revisions

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-{{STRUCTURE_1aw6|  PDB=1aw6  |  SCENE=  }}
+==GAL4 (CD), NMR, 24 STRUCTURES==
-===GAL4 (CD), NMR, 24 STRUCTURES===
+<StructureSection load='1aw6' size='340' side='right' caption='[[1aw6]], [[NMR_Ensembles_of_Models | 24 NMR models]]' scene=''>
-{{ABSTRACT_PUBMED_9460244}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1aw6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=125d 125d]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AW6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AW6 FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene><br>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aw6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1aw6 RCSB], [http://www.ebi.ac.uk/pdbsum/1aw6 PDBsum]</span></td></tr>
+<table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aw/1aw6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+We have refined the solution structure of cadmium-bound GAL4 and present its 15N and 1H NMR assignments. The root-mean-square (rms) deviation to the average structure was 0.4 +/- 0.05 A for backbone atoms, and 0.9 +/- 0.1 A for all heavy atoms. The three-bond heteronuclear 3J(113Cd,1H) coupling constants were found to disobey a Karplus-type relationship, which was attributable to the unusual constraints imposed by the bimetal-thiolate cluster in GAL4. We conclude that the structural parameters that correlate to 3J(113Cd,1H) are complex.
-==About this Structure==
+Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination.,Baleja JD, Thanabal V, Wagner G J Biomol NMR. 1997 Dec;10(4):397-401. PMID:9460244<ref>PMID:9460244</ref>
-[[1aw6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=125d 125d]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AW6 OCA].
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
 ==See Also==
-*[[Gal4|Gal4]]
+*[[Gal3-Gal80-Gal4|Gal3-Gal80-Gal4]]
 *[[Journal:JBIC:9|Journal:JBIC:9]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:009460244</ref><ref group="xtra">DOI 10.1007/s00775-011-0770-2</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
 [[Category: Saccharomyces cerevisiae]]
 [[Category: Baleja, J D.]]