1g2i: Difference between revisions

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Revision as of 12:17, 20 March 2008

File:1g2i.gif

, resolution 2.00Å

Ligands:

Gene:

PH1704 (Pyrococcus horikoshii)

Coordinates:

save as pdb, mmCIF, xml

CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION

OverviewOverview

The intracellular protease from Pyrococcus horikoshii (PH1704) and PfpI from Pyrococcus furiosus are members of a class of intracellular proteases that have no sequence homology to any other known protease family. We report the crystal structure of PH1704 at 2.0-A resolution. The protease is tentatively identified as a cysteine protease based on the presence of cysteine (residue 100) in a nucleophile elbow motif. In the crystal, PH1704 forms a hexameric ring structure, and the active sites are formed at the interfaces between three pairs of monomers.

About this StructureAbout this Structure

1G2I is a Single protein structure of sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA.

ReferenceReference

Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution., Du X, Choi IG, Kim R, Wang W, Jancarik J, Yokota H, Kim SH, Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14079-84. PMID:11114201

Page seeded by OCA on Thu Mar 20 11:17:17 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1g2i.gif|left|200px]]<br /><applet load="1g2i" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1g2i.gif|left|200px]]
-caption="1g2i, resolution 2.00&Aring;" />
-'''CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION'''<br />
+ {{Structure
+|PDB= 1g2i |SIZE=350|CAPTION= <scene name='initialview01'>1g2i</scene>, resolution 2.00&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
+|ACTIVITY=
+|GENE= PH1704 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
+}}
+'''CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-G2I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2I OCA].
+G2I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2I OCA].
 ==Reference==
-Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution., Du X, Choi IG, Kim R, Wang W, Jancarik J, Yokota H, Kim SH, Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14079-84. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11114201 11114201]
+Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution., Du X, Choi IG, Kim R, Wang W, Jancarik J, Yokota H, Kim SH, Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14079-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11114201 11114201]
 [[Category: Pyrococcus horikoshii]]
 [[Category: Single protein]]
@@ Line 31: / Line 40: @@
 [[Category: protein structure initiative]]
 [[Category: psi]]
-[[Category: structural genomics]]
+[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:45:21 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:17:17 2008''