2f8a: Difference between revisions

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[[Image:2f8a.png|left|200px]]
==Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1==
 
<StructureSection load='2f8a' size='340' side='right' caption='[[2f8a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
{{STRUCTURE_2f8a|  PDB=2f8a  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2f8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F8A FirstGlance]. <br>
===Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene><br>
 
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GPX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
{{ABSTRACT_PUBMED_016754991}}
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] </span></td></tr>
 
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2f8a RCSB], [http://www.ebi.ac.uk/pdbsum/2f8a PDBsum]</span></td></tr>
==About this Structure==
<table>
[[2f8a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8A OCA].  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/2f8a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Glutathione peroxidase|Glutathione peroxidase]]
*[[Glutathione peroxidase|Glutathione peroxidase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:016754991</ref><references group="xtra"/>
[[Category: Glutathione peroxidase]]
[[Category: Glutathione peroxidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 05:59, 29 September 2014

Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1

Structural highlights

2f8a is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:GPX1 (Homo sapiens)
Activity:Glutathione peroxidase, with EC number 1.11.1.9
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2f8a, resolution 1.50Å

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