1fw4: Difference between revisions
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[[Image:1fw4.gif|left|200px]] | [[Image:1fw4.gif|left|200px]] | ||
'''CRYSTAL STRUCTURE OF E. COLI FRAGMENT TR2C FROM CALMODULIN TO 1.7 A RESOLUTION''' | {{Structure | ||
|PDB= 1fw4 |SIZE=350|CAPTION= <scene name='initialview01'>1fw4</scene>, resolution 1.7Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''CRYSTAL STRUCTURE OF E. COLI FRAGMENT TR2C FROM CALMODULIN TO 1.7 A RESOLUTION''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1FW4 is a [ | 1FW4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry 1TRC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FW4 OCA]. | ||
==Reference== | ==Reference== | ||
Structure of Escherichia coli fragment TR2C from calmodulin to 1.7 A resolution., Olsson LL, Sjolin L, Acta Crystallogr D Biol Crystallogr. 2001 May;57(Pt 5):664-9. Epub 2001, Apr 24. PMID:[http:// | Structure of Escherichia coli fragment TR2C from calmodulin to 1.7 A resolution., Olsson LL, Sjolin L, Acta Crystallogr D Biol Crystallogr. 2001 May;57(Pt 5):664-9. Epub 2001, Apr 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11320306 11320306] | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: tr2c]] | [[Category: tr2c]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:14:47 2008'' | ||
Revision as of 12:14, 20 March 2008
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF E. COLI FRAGMENT TR2C FROM CALMODULIN TO 1.7 A RESOLUTION
OverviewOverview
Fragment TR2C is the C-terminal part of the calcium-binding protein calmodulin, including residues 78-148. The crystal structure of TR2C was solved by molecular replacement and refined to a conventional R value of 21.8% (R(free) = 22.0%), using all data in the resolution range 20.0-1.7 A. This study shows that the secondary structure of TR2C, a pair of EF-hand motifs with two calcium-binding sites, is similar to the corresponding motifs in intact calmodulin. However, it also indicates that the N-terminus of helix E is closer to the C-terminus of helix H in TR2C than in the intact protein and that the loop connecting the EF-hands shows different conformations in the two structures. The crystal structure of TR2C was further found to be similar to the set of NMR structures of this fragment, although some pronounced differences exist.
About this StructureAbout this Structure
1FW4 is a Single protein structure of sequence from Bos taurus. This structure supersedes the now removed PDB entry 1TRC. Full crystallographic information is available from OCA.
ReferenceReference
Structure of Escherichia coli fragment TR2C from calmodulin to 1.7 A resolution., Olsson LL, Sjolin L, Acta Crystallogr D Biol Crystallogr. 2001 May;57(Pt 5):664-9. Epub 2001, Apr 24. PMID:11320306
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