1fq6: Difference between revisions
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[[Image:1fq6.jpg|left|200px]] | [[Image:1fq6.jpg|left|200px]] | ||
'''X-RAY STRUCTURE OF GLYCOL INHIBITOR PD-133,450 BOUND TO SACCHAROPEPSIN''' | {{Structure | ||
|PDB= 1fq6 |SIZE=350|CAPTION= <scene name='initialview01'>1fq6</scene>, resolution 2.7Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=SOT:N-HYDROSULFONYLMORPHOLINE'>SOT</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=GSC:2-ETHYLTHIO+GLYCINE'>GSC</scene> and <scene name='pdbligand=XAO:CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE'>XAO</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Saccharopepsin Saccharopepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.25 3.4.23.25] | |||
|GENE= | |||
}} | |||
'''X-RAY STRUCTURE OF GLYCOL INHIBITOR PD-133,450 BOUND TO SACCHAROPEPSIN''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1FQ6 is a [ | 1FQ6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FQ6 OCA]. | ||
==Reference== | ==Reference== | ||
X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity., Cronin NB, Badasso MO, J Tickle I, Dreyer T, Hoover DJ, Rosati RL, Humblet CC, Lunney EA, Cooper JB, J Mol Biol. 2000 Nov 10;303(5):745-60. PMID:[http:// | X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity., Cronin NB, Badasso MO, J Tickle I, Dreyer T, Hoover DJ, Rosati RL, Humblet CC, Lunney EA, Cooper JB, J Mol Biol. 2000 Nov 10;303(5):745-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11061973 11061973] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Saccharopepsin]] | [[Category: Saccharopepsin]] | ||
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[[Category: 4-dihydroxy-6-methylheptane).]] | [[Category: 4-dihydroxy-6-methylheptane).]] | ||
[[Category: 4s) 2-amino-1cyclohexyl-3]] | [[Category: 4s) 2-amino-1cyclohexyl-3]] | ||
[[Category: diol moiety spanning p1-p1' inhibitor sites (acdmh - ( | [[Category: diol moiety spanning p1-p1' inhibitor sites (acdmh - (2]] | ||
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