Severin: Difference between revisions

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[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well.   
[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well.   


== 3D Structures of Severin ==
== 3D Structures of Severin ==
[[3fg6]] – Adseverin C-terminal – human<br />
[[3fg6]] – Adseverin C-terminal – human<br />
[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br />
[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br />
[[1svq]], [[1svr]] - DdSeverin domain 2 - ''Dictyostelium discoideum'', NMR<br />
[[1svq]], [[1svr]] - DdSeverin domain 2 - NMR<br />


[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky