Protein phosphatase: Difference between revisions
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{{STRUCTURE_3k7v| PDB=3k7v | SIZE=400| SCENE= |right|CAPTION=Human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin and sulfate [[3k7v]] }} | {{STRUCTURE_3k7v| PDB=3k7v | SIZE=400| SCENE= |right|CAPTION=Human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin and sulfate [[3k7v]] }} | ||
'''Protein phosphatases''' (PP) regular protein phosphorylation and thus are key in intracellular signal transduction processes. | '''Protein phosphatases''' (PP) regular protein phosphorylation and thus are key in intracellular signal transduction processes.<br /> | ||
* '''PP1''' is a serine/threonine phosphatase.<br /> | |||
* '''PP2A''' targets proteins in the oncogenic signaling pathways. For PP2A see also [[HEAT Repeat]].<br /> | |||
* '''PP2C''' are Mg/Mn- dependent and are essential for the regulation of cell cycle and stress signaling pathways.<br /> | |||
* '''PP4''' regulates a variety of cellular functions.<br /> | |||
* '''PP5''' is activated by lipids and is involved in signal transduction. | |||
== 3D Structures of protein phosphatase== | == 3D Structures of protein phosphatase== |