Backbone representations: Difference between revisions

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==Protein Main Chain==
==Protein Main Chain==


Here is a small alpha helix (15 amino acids)<ref>Residues 23-37 from [[1pgb]].</ref> In the <scene name='59/599354/Helix/1'>initial scene</scene>, all atoms are shown.
Here is a small alpha helix (15 amino acids)<ref>Residues 23-37 from [[1pgb]].</ref> In the <scene name='59/599354/Helix/1'>initial scene</scene>, all atoms are shown, colored by element:
<font style="font-size:150%;">{{Template:ColorKey_Element_C}}
{{Template:ColorKey_Element_H}}
{{Template:ColorKey_Element_O}}
{{Template:ColorKey_Element_N}}</font>.


*First, we'll simplify by <scene name='59/599354/Helix/2'>hiding the hydrogen atoms</scene>. [[Hydrogen]] atoms make up almost exactly 50% of the atoms in proteins.
*First, we'll simplify by <scene name='59/599354/Helix/2'>hiding the hydrogen atoms</scene>. [[Hydrogen in macromolecular models|Hydrogen]] atoms make up almost exactly 50% of the atoms in proteins.


*Next, we'll simplify by <scene name='59/599354/Helix/3'>hiding the amino acid side chains</scene>. What remains is called the main chain. Each amino acid's main chain atoms are N-C-C, where the first C is the alpha carbon, and the second, the carboxyl carbon with its double-bonded oxygen (double bonds not shown). We could also <scene name='59/599354/Helix/4'>hide the oxygen atoms</scene>, leaving only the atoms that are part of the '''main chain''', also called the backbone.
*Next, we'll simplify by <scene name='59/599354/Helix/3'>hiding the amino acid side chains</scene>. What remains is called the main chain. Each amino acid's main chain atoms are N-C-C, where the first C is the alpha carbon, and the second, the carboxyl carbon with its double-bonded oxygen (double bonds not shown). We could also <scene name='59/599354/Helix/4'>hide the oxygen atoms</scene>, leaving only the atoms that are part of the '''main chain''', also called the backbone.

Revision as of 20:13, 19 September 2014

Backbone representations are simplified 3D depictions of proteins or nucleic acids that enable the polymer chain structure to be seen.


Protein Main Chain

Here is a small alpha helix (15 amino acids)[1] In the , all atoms are shown, colored by element:

C H O N.

  • First, we'll simplify by . Hydrogen atoms make up almost exactly 50% of the atoms in proteins.
  • Next, we'll simplify by . What remains is called the main chain. Each amino acid's main chain atoms are N-C-C, where the first C is the alpha carbon, and the second, the carboxyl carbon with its double-bonded oxygen (double bonds not shown). We could also , leaving only the atoms that are part of the main chain, also called the backbone.

Protein Backbone Trace

Backbone Trace


Drag the structure with the mouse to rotate

ReferencesReferences

  1. Residues 23-37 from 1pgb.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Eric Martz, Margaret Franzen