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''' | ==Crystal structure of murine IRE1 in complex with MKC9989 inhibitor== | ||
<StructureSection load='4pl3' size='340' side='right' caption='[[4pl3]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4pl3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PL3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PL3 FirstGlance]. <br> | |||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=31J:7-HYDROXY-6-METHOXY-3-[2-(2-METHOXYETHOXY)ETHYL]-4,8-DIMETHYL-2H-CHROMEN-2-ONE'>31J</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br> | |||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pl4|4pl4]], [[4pl5|4pl5]]</td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pl3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pl3 RCSB], [http://www.ebi.ac.uk/pdbsum/4pl3 PDBsum]</span></td></tr> | |||
<table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Al-awar, R.]] | |||
[[Category: Chiovitti, D.]] | |||
[[Category: Duffy, N.]] | |||
[[Category: Patterson, J B.]] | |||
[[Category: Sanches, M.]] | |||
[[Category: Sicheri, F.]] | |||
[[Category: Talukdar, M.]] | |||
[[Category: Thevakumaran, N.]] | |||
[[Category: Endoribonuclease]] | |||
[[Category: Hydrolase-inhibitor complex]] | |||
[[Category: Inhibitor complex]] | |||
[[Category: Schiff base]] | |||
[[Category: Transferase]] | |||
[[Category: Unfolded protein response]] |
Revision as of 09:10, 4 September 2014
Crystal structure of murine IRE1 in complex with MKC9989 inhibitorCrystal structure of murine IRE1 in complex with MKC9989 inhibitor
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