Ion channels: Difference between revisions
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Voltage-Dependent Calcium Channels (VDCC) allow Ca to enter the cell resulting in muscle contraction, neuron excitation or hormone release. VDCC are composed of several subunits and are named as a Cav gene product. The human annexin V molecule serves as a calcium channel. There are also Voltage-Dependent Anion Channels (VDAC). Chloride ion channels (ClCh) are involved in maintaining pH, volume homeostasis and more. Ligand-Gated Ion Channels (LGIC) open or close when binding a ligand like a neurotransmitter. The Cyclic Nucleotide-Gated channel (CNGC) conduct cations upon binding of cAMP or cGMP. The Acid-Sensitive channels (ASC) conduct cations upon binding of acid. The glycerol facilitator (GlpF) is a protein channel which transports glycerol across the cell membrane of ''E. coli''. Other ion channel proteins are the aquaporins, gramicidin, antiamoebin, trichotoxin, peptaibol and the glutamate receptor. | Voltage-Dependent Calcium Channels (VDCC) allow Ca to enter the cell resulting in muscle contraction, neuron excitation or hormone release. VDCC are composed of several subunits and are named as a Cav gene product. The human annexin V molecule serves as a calcium channel. There are also Voltage-Dependent Anion Channels (VDAC). Chloride ion channels (ClCh) are involved in maintaining pH, volume homeostasis and more. Ligand-Gated Ion Channels (LGIC) open or close when binding a ligand like a neurotransmitter. The Cyclic Nucleotide-Gated channel (CNGC) conduct cations upon binding of cAMP or cGMP. The Acid-Sensitive channels (ASC) conduct cations upon binding of acid. The glycerol facilitator (GlpF) is a protein channel which transports glycerol across the cell membrane of ''E. coli''. Other ion channel proteins are the aquaporins, gramicidin, antiamoebin, trichotoxin, peptaibol and the glutamate receptor. | ||
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=== Potassium channel === | === Potassium channel === | ||
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===Nicotinic acetylcholine receptor=== | ===Nicotinic acetylcholine receptor=== | ||
[[1oed]], [[2bg9]] - AChR - ''Torpeco marmorata'' - EM<br /> | [[1oed]], [[2bg9]], [[4bor]] - AChR - ''Torpeco marmorata'' - EM<br /> | ||
[[2k58]] - AChR β2 subunit 1st transmembrane domain - NMR<br /> | [[2k58]] - AChR β2 subunit 1st transmembrane domain - NMR<br /> | ||
[[2k59]] - AChR β2 subunit - NMR | [[2k59]] - AChR β2 subunit - NMR | ||