Fibroblast growth factor: Difference between revisions

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'''Fibroblast growth factors''' (FGF) are involved in angiogenesis, wound-healing and embryonic development.  FGF is heparin-binding protein.  FGF require heparan sulfate (HS) to activate the four FGF cell-surface receptors (FGFR).  In vertebrates there are 23 members in the FGF family.  FGF signaling is important in the pathogenesis of a variety of tumor types.  FGF1 is called acidic FGF while FGF2 is called basic FGF.  FGF7 is called keratinocyte growth factor which is present in the eiptheliazation-phase of wound healing when keratinocytes are covering the wound.
'''Fibroblast growth factors''' (FGF) are involved in angiogenesis, wound-healing and embryonic development.  FGF is heparin-binding protein.  FGF require heparan sulfate (HS) to activate the four FGF cell-surface receptors (FGFR).  In vertebrates there are 23 members in the FGF family.  FGF signaling is important in the pathogenesis of a variety of tumor types.<br />
* '''FGF1''' is called acidic FGF.<br />
*  '''FGF2''' is called basic FGF.<br />
* '''FGF7''' is called keratinocyte growth factor which is present in the eiptheliazation-phase of wound healing when keratinocytes are covering the wound.


==3D structures of fibroblast growth factor==
==3D structures of fibroblast growth factor==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky