Cadherin: Difference between revisions

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[[Image:1q1p.png|left|200px|thumb|Crystal Structure of Cadherin, [[1q1p]]]]
 
{{STRUCTURE_1q1p|  PDB=1q1p  | SIZE=400| SCENE=Cadherin/Cv/1 |right|CAPTION=Epithelial cadherin complex with Ca+2 ions, [[1q1p]] }}
{{STRUCTURE_1q1p|  PDB=1q1p  | SIZE=400| SCENE=Cadherin/Cv/1 |right|CAPTION=Epithelial cadherin complex with Ca+2 ions, [[1q1p]] }}


 
[[Cadherin|Cadherins]] (CDH) are calcium-dependent adhesion proteins.  They contain extracellular CDH repeats (EC1-EC5) which bind calcium ions.  They are encoded by numerous genes numbered CDH1-CDH23.  Some names of CDH indicate their locations: E-CDH (epithelial tissue), VE-CDH (vascular epithelial), T-CDH bound to membrane, N-CDH (neurons).  The CDH superfamily contains protocadhedrins (Prot-CDH), desmogleins (Des-CDH) and more.   Calcium ions are shown as a space filling objects.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
[[Cadherin|Cadherins]] (CDH) are calcium-dependent adhesion proteins.  They contain extracellular CDH repeats (EC1-EC5) which bind calcium ions.  They are encoded by numerous genes numbered CDH1-CDH23.  Some names of CDH indicate their locations: E-CDH (epithelial tissue), VE-CDH (vascular epithelial), T-CDH bound to membrane, N-CDH (neurons).  The CDH superfamily contains protocadhedrins (Prot-CDH), desmogleins (Des-CDH) and more. The images at the left and at the right correspond to one representative Cadherin, ''i.e.'' the crystal structure of Cadherin ([[1q1p]]).  Calcium ions is shown as a space filling objects.


== 3D Structures of Cadherin ==
== 3D Structures of Cadherin ==

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Alexander Berchansky, Michal Harel