Thioredoxin: Difference between revisions

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[[Thioredoxin]] (Trx) is an enzyme which facilitates the reduction of proteins by cysteine thiol-disulfide exchange.  They contain a CXXC motif. Trx-1 is a mammalian cellular protein.  Trx-2 is mitochondria-specific. In higher plants, Trx are divided to 6 groups based on their sequence.  Trx  M, X and Y are found in prokaryotes while F, H and O are found in eukaryotes. The images at the left and at the right correspond to one representative Trx, ''i.e.'' the crystal structure of human Thioredoxin ([[1ert]]).
[[Thioredoxin]] (Trx) is an enzyme which facilitates the reduction of proteins by cysteine thiol-disulfide exchange.  They contain a CXXC motif.<br />
* '''Trx-1''' is a mammalian cellular protein.<br />
* '''Trx-2''' is mitochondria-specific.<br />
In higher plants, Trx are divided to 6 groups based on their sequence.  Trx  M, X and Y are found in prokaryotes while F, H and O are found in eukaryotes.  


== 3D Structures of Thioredoxin ==
== 3D Structures of Thioredoxin ==

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Alexander Berchansky, Michal Harel, Joel L. Sussman