1dg7: Difference between revisions

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-[[Image:1dg7.gif|left|200px]]<br /><applet load="1dg7" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1dg7.gif|left|200px]]
-caption="1dg7, resolution 1.8&Aring;" />
-'''DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND 4-BROMO WR99210'''<br />
+ {{Structure
+|PDB= 1dg7 |SIZE=350|CAPTION= <scene name='initialview01'>1dg7</scene>, resolution 1.8&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=WRB:1-[3-(4-BROMO-PHENOXY)-PROPOXY]-6,6-DIMETHYL-1.6-DIHYDRO-[1,3,5]TRIAZINE-2,4-DIAMINE'>WRB</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]
+|GENE=
+}}
+'''DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND 4-BROMO WR99210'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-DG7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=WRB:'>WRB</scene>, <scene name='pdbligand=NDP:'>NDP</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DG7 OCA].
+DG7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DG7 OCA].
 ==Reference==
-Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs., Li R, Sirawaraporn R, Chitnumsub P, Sirawaraporn W, Wooden J, Athappilly F, Turley S, Hol WG, J Mol Biol. 2000 Jan 14;295(2):307-23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10623528 10623528]
+Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs., Li R, Sirawaraporn R, Chitnumsub P, Sirawaraporn W, Wooden J, Athappilly F, Turley S, Hol WG, J Mol Biol. 2000 Jan 14;295(2):307-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10623528 10623528]
 [[Category: Dihydrofolate reductase]]
 [[Category: Mycobacterium tuberculosis]]
@@ Line 27: / Line 36: @@
 [[Category: anti-malaria agent]]
 [[Category: dihydrofolate reductase]]
-[[Category: folateanalogs]]
+[[Category: folateanalog]]
 [[Category: nicotinamide adenine dinucleotide]]
 [[Category: rossmann fold]]
@@ Line 34: / Line 43: @@
 [[Category: wr99210]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:16:19 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:38:03 2008''