Uridine 5'-monophosphate synthase: Difference between revisions
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{{STRUCTURE_2v30| PDB=2v30 | SIZE=400| SCENE= |right|CAPTION=Human uridine 5'-monophosphate synthase OPD subunit dimer complex with UMP (stick model), [[2v30]] }} | {{STRUCTURE_2v30| PDB=2v30 | SIZE=400| SCENE= |right|CAPTION=Human uridine 5'-monophosphate synthase OPD subunit dimer complex with UMP (stick model), [[2v30]] }} | ||
'''Uridine 5’-monophosphate synthase''' (UMPS) is a bifunctional enzyme catalyzes the formation of uridine monophosphate (UMP). UMPS N-terminal domain is an orotate phosphoribosyl transferase (OPRT) subunit which catalyzes the addition of ribose-phosphate to orotate forming orotidine 5’-monophosphate (OMP). The C-terminal subunit is orotidine 5’-phosphate decarboxylase (OPD) which decarboxylates OMP to form UMP. | '''Uridine 5’-monophosphate synthase''' (UMPS) is a bifunctional enzyme catalyzes the formation of uridine monophosphate (UMP). UMPS N-terminal domain is an '''orotate phosphoribosyl transferase''' (OPRT) subunit which catalyzes the addition of ribose-phosphate to orotate forming orotidine 5’-monophosphate (OMP). The C-terminal subunit is '''orotidine 5’-phosphate decarboxylase''' (OPD) which decarboxylates OMP to form UMP. | ||
===3D structures of uridine 5'-monophosphate synthase=== | ===3D structures of uridine 5'-monophosphate synthase=== | ||