1cqe: Difference between revisions

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[[Image:1cqe.gif|left|200px]]<br /><applet load="1cqe" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1cqe.gif|left|200px]]
caption="1cqe, resolution 3.1&Aring;" />
 
'''PROSTAGLANDIN H2 SYNTHASE-1 COMPLEX WITH FLURBIPROFEN'''<br />
{{Structure
|PDB= 1cqe |SIZE=350|CAPTION= <scene name='initialview01'>1cqe</scene>, resolution 3.1&Aring;
|SITE= <scene name='pdbsite=COA:Hydrophobic+Channel+Responsible+For+Cycloogenase+Activity'>COA</scene>, <scene name='pdbsite=COB:Hydrophobic+Channel+Responsible+For+Cycloogenase+Activity'>COB</scene>, <scene name='pdbsite=POA:Heme+Pocket+Responsible+For+Peroxidase+Activity'>POA</scene> and <scene name='pdbsite=POB:Heme+Pocket+Responsible+For+Peroxidase+Activity'>POB</scene>
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> and <scene name='pdbligand=FLP:FLURBIPROFEN'>FLP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1]
|GENE=
}}
 
'''PROSTAGLANDIN H2 SYNTHASE-1 COMPLEX WITH FLURBIPROFEN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1CQE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=FLP:'>FLP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] Known structural/functional Sites: <scene name='pdbsite=COA:Hydrophobic+Channel+Responsible+For+Cycloogenase+Activity'>COA</scene>, <scene name='pdbsite=COB:Hydrophobic+Channel+Responsible+For+Cycloogenase+Activity'>COB</scene>, <scene name='pdbsite=POA:Heme+Pocket+Responsible+For+Peroxidase+Activity'>POA</scene> and <scene name='pdbsite=POB:Heme+Pocket+Responsible+For+Peroxidase+Activity'>POB</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CQE OCA].  
1CQE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CQE OCA].  


==Reference==
==Reference==
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1., Picot D, Loll PJ, Garavito RM, Nature. 1994 Jan 20;367(6460):243-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8121489 8121489]
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1., Picot D, Loll PJ, Garavito RM, Nature. 1994 Jan 20;367(6460):243-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8121489 8121489]
[[Category: Ovis aries]]
[[Category: Ovis aries]]
[[Category: Prostaglandin-endoperoxide synthase]]
[[Category: Prostaglandin-endoperoxide synthase]]
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[[Category: peroxidase]]
[[Category: peroxidase]]


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