1c70: Difference between revisions

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-[[Image:1c70.gif|left|200px]]<br /><applet load="1c70" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1c70.gif|left|200px]]
-caption="1c70, resolution 2.5&Aring;" />
-'''ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.'''<br />
+ {{Structure
+|PDB= 1c70 |SIZE=350|CAPTION= <scene name='initialview01'>1c70</scene>, resolution 2.5&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=L75:N-[2(R)-HYDROXY-1(S)-INDANYL]-2(R)-PHENYLMETHYL-4(S)-HYDROXY-5-[4-[2-BENZOFURANYLMETHYL]-2(S)-[TERT-BUTYLAMINOCARBONYL]-PIPERAZINYL]-PENTANEAMIDE'>L75</scene>
+|ACTIVITY=
+|GENE= NY5 ISOLATE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
+}}
+'''ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-C70 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=L75:'>L75</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C70 OCA].
+C70 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C70 OCA].
 ==Reference==
-An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease., Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC, Acta Crystallogr D Biol Crystallogr. 2000 Apr;56(Pt 4):381-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10739910 10739910]
+An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease., Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC, Acta Crystallogr D Biol Crystallogr. 2000 Apr;56(Pt 4):381-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10739910 10739910]
 [[Category: Human immunodeficiency virus 1]]
 [[Category: Single protein]]
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 [[Category: hydrolase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:03:10 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:20:41 2008''