1c2t: Difference between revisions

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-[[Image:1c2t.jpg|left|200px]]<br /><applet load="1c2t" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1c2t.jpg|left|200px]]
-caption="1c2t, resolution 2.10&Aring;" />
-'''NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.'''<br />
+ {{Structure
+|PDB= 1c2t |SIZE=350|CAPTION= <scene name='initialview01'>1c2t</scene>, resolution 2.10&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NHS:10-FORMYL-5,8,10-TRIDEAZAFOLIC+ACID'>NHS</scene> and <scene name='pdbligand=GAR:GLYCINAMIDE RIBONUCLEOTIDE'>GAR</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphoribosylglycinamide_formyltransferase Phosphoribosylglycinamide formyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.2 2.1.2.2]
+|GENE=
+}}
+'''NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-C2T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NHS:'>NHS</scene> and <scene name='pdbligand=GAR:'>GAR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphoribosylglycinamide_formyltransferase Phosphoribosylglycinamide formyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.2 2.1.2.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C2T OCA].
+C2T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C2T OCA].
 ==Reference==
-New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid., Greasley SE, Yamashita MM, Cai H, Benkovic SJ, Boger DL, Wilson IA, Biochemistry. 1999 Dec 21;38(51):16783-93. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10606510 10606510]
+New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid., Greasley SE, Yamashita MM, Cai H, Benkovic SJ, Boger DL, Wilson IA, Biochemistry. 1999 Dec 21;38(51):16783-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10606510 10606510]
 [[Category: Escherichia coli]]
 [[Category: Phosphoribosylglycinamide formyltransferase]]
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 [[Category: purine biosynthesis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:01:50 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:19:06 2008''