1bzc: Difference between revisions

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[[Image:1bzc.jpg|left|200px]]<br /><applet load="1bzc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1bzc.jpg|left|200px]]
caption="1bzc, resolution 2.35&Aring;" />
 
'''HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI'''<br />
{{Structure
|PDB= 1bzc |SIZE=350|CAPTION= <scene name='initialview01'>1bzc</scene>, resolution 2.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TPI:4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID'>TPI</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
|GENE=
}}
 
'''HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1BZC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TPI:'>TPI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BZC OCA].  
1BZC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BZC OCA].  


==Reference==
==Reference==
Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics., Groves MR, Yao ZJ, Roller PP, Burke TR Jr, Barford D, Biochemistry. 1998 Dec 22;37(51):17773-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9922143 9922143]
Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics., Groves MR, Yao ZJ, Roller PP, Burke TR Jr, Barford D, Biochemistry. 1998 Dec 22;37(51):17773-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9922143 9922143]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: tyrosine phosphatase]]
[[Category: tyrosine phosphatase]]


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