1bl0: Difference between revisions

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Revision as of 11:12, 20 March 2008

File:1bl0.gif

, resolution 2.300Å

Gene:

MARA (Escherichia coli)

Coordinates:

save as pdb, mmCIF, xml

MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX

OverviewOverview

A crystal structure for a member of the AraC prokaryotic transcriptional activator family, MarA, in complex with its cognate DNA-binding site is described. MarA consists of two similar subdomains, each containing a helix-turn-helix DNA-binding motif. The two recognition helices of the motifs are inserted into adjacent major groove segments on the same face of the DNA but are separated by only 27 A thereby bending the DNA by approximately 35 degrees. Extensive interactions between the recognition helices and the DNA major groove provide the sequence specificity.

About this StructureAbout this Structure

1BL0 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator., Rhee S, Martin RG, Rosner JL, Davies DR, Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8. PMID:9724717

Page seeded by OCA on Thu Mar 20 10:12:27 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1bl0.gif|left|200px]]<br /><applet load="1bl0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1bl0.gif|left|200px]]
-caption="1bl0, resolution 2.300&Aring;" />
-'''MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX'''<br />
+ {{Structure
+|PDB= 1bl0 |SIZE=350|CAPTION= <scene name='initialview01'>1bl0</scene>, resolution 2.300&Aring;
+|SITE=
+|LIGAND=
+|ACTIVITY=
+|GENE= MARA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+}}
+'''MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-BL0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BL0 OCA].
+BL0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BL0 OCA].
 ==Reference==
-A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator., Rhee S, Martin RG, Rosner JL, Davies DR, Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9724717 9724717]
+A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator., Rhee S, Martin RG, Rosner JL, Davies DR, Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9724717 9724717]
 [[Category: Escherichia coli]]
 [[Category: Single protein]]
@@ Line 19: / Line 28: @@
 [[Category: transcriptional activator; a bipartite helix-turn-helix protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:56:25 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:12:27 2008''